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微囊藻毒素及其与原发性肝癌的关系 被引量:5

Microcystins and its Relationship with the Occurrence of Primary Liver Cancer
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作者 罗皓 张志勇
出处 《中国慢性病预防与控制》 CAS 2004年第6期278-280,共3页 Chinese Journal of Prevention and Control of Chronic Diseases
基金 广西区教育厅及广西医科大学资助项目(桂科教19982-8)
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  • 1Ueno Y.Detection of microcystins,a blue-green alga hepatotoxin,in drinking water sampled in Haimen and Fusui,endemic areas of primary liver cancer in China,by highly sensitive immunoassav [J].Carcinogensis,1996,17:1317-1321.
  • 2Sekijima M, Tsutsumi T, Yoshinori T, et al. Enhancement of gluta-thione S-transferase placental-form positive liver cell foci development by microcystin-LR in aflatoxin B1-initiated rats [J].Carcinogenesis, 1999,20:161-165.
  • 3Bagu JR. Amolecular basis for different interactions of marine toxins with protein phosphatase-1, molecular models for bound motuporin,microcystins, okadaic acid and calyculin A[J]. J Biol Chem, 1997,72:5087-5097.
  • 4Rivasseau G,Martins S,Hennion MC. Determination of some physicochemical parameters of microcysins (cyanobacetrial toxins) and trace level analysis in environmental samples using liquid chromatography[J]. J Chromatogr A, 1998,799 ( 1-2): 155-169.
  • 5Suzuki H,Watanabe MF,Wu Y,et al. Mutagenicity of microcystinLR in human Rsa cells[J]. Int J Mol Med,1998,2:109-112.
  • 6Ding WX, Shen HM, Zhu HG, et al. Genotoxicity of microcystic cyano-bacteria extract of a water source in China [J]. Mutation Res-earch, 1999,42:69-77.
  • 7Zegura B, Sedmak B, Filipic M. Microcystin-LR induces oxidative DNA damage in human hepatoma cell line HepG2[J].Toxicon,2003,41:41-48.
  • 8Pouria S, Andrade A, Barbosa J, et al. Fatal microcystin intoxication in haemodialysis unit in Caruaru, Brazil[J]. Lancet, 1998,352:21-26.
  • 9Dawson RM. The toxicology of microcystins[J]. Toxicon,1998, 36:953-962.
  • 10Cousins IT, Bcaling DJ, James HA, et al. Biodegradation of microcystin-LR by indigenous mixed bacterial populations [J].Water Res, 1996,30:481-484.

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