摘要
目的 :探讨双胶润通胶囊的润肠通便作用的效果及剂量。方法 :实验采用动物试验 ,将小白鼠 (雌雄各半 ,体重 18～ 2 2g)分成两个实验组 ,每组 5 0只 ,实验一组进行小肠推进试验 ,实验二组进行排便试验 ,时间均为 7d。按推荐剂量每人每日 5g设计 ,分为低、中、高 3个剂量组 ,另设空白对照和模型对照组。结果 :在不影响小鼠体重的情况下 ,双胶润通胶囊高剂量组小肠推进率与模型对照组比较差异均有显著性变化 (P <0 .0 5 ) ;3个剂量组小鼠的首便时间、粪便粒数均高于便秘模型对照组 ,差异具有极显著性差异 (P <0 .0 1) ;结论 :双胶润通胶囊对小鼠小肠运动有增强作用 ,并能缩短小鼠首便时间、增加小鼠的粪便粒数与重量 ,即 :具有润肠通便作用。
Objective:Discussion in the Shuangjiaoruntong capsule's effect and dose to moisten the intestine and to free the stool. Methods:Animal experiment was adopted in this paper,the mice (weight 18～22 g) were divided by two trail groups with 50 mice in each group. The first group engaged in the small intestine propulsive experiment and the second one engaged in the defecation experiment with the trail time 7days respectively. According to the recommended dose-5 g a day per person designed,it was divided into the low,middle and high three dose groups,as well as blank group and model group. Result:When the mouse weight is not effected,compared to the model group,the efficiency of the small intestine propulsion of the high dose group is significant( P <0.05);compared to the model group,the first stool time and the fecal quantity of the mouse in the three groups have high significance( P <0.01).Conclusion:The Shuangjiaoruntong capsule has the function of moistening the intestines and freeing the stool.
出处
《中国野生植物资源》
2004年第6期43-45,共3页
Chinese Wild Plant Resources
基金
国家十五攻关重点项目 (2 0 0 4BA5 0 2B0 3)
关键词
小鼠
胶囊
对照组
高剂量
润肠通便作用
实验
便秘模型
粒数
粪便
体重
Shuangjiaoruntong capsule
Moisten the intestine and free the stool
Refined Konjac meal
Experimental study
