摘要
目的 :研究血压变异 (BPV)与心率变异 (HRV)及心电图 (ECG)异常相关性 .方法 :对 15 7例未经治疗的早期高血压患者及 16 7例未服过影响血压及心率药物的正常人 ,进行BPV、HRV及ECG异常的相关分析 ,各种数据在同一时刻得到 .结果 :当血压昼夜节律消失 (非杓型 ) ,BPV及HRV不正常 ,ECG异常明显高于其他组 .当高血压患者血压昼夜节律存在时HRV各项指标接近正常 ,ECG异常率较低 .HRV降低与血压负荷升高呈明显正相关 ,与心电异常也呈明显正相关 .结论 :对高血压治疗的目的 ,不仅仅是降压 ,还应尽量恢复昼夜血压的规律性 ,降低夜间血压负荷 ,调节植物神经功能 .对于血压正常的患者 ,血压昼夜节律消失也应投以关照给予植物神经功能调节 ,达到或降低靶器官损伤或延缓靶器官损害的目的 ,提高患者的生活质量 .
Objective: To investigate the changes of ambulatory blood pressure variability (BPV), heart rate variability (HRV) and electrocardiogram in essential hypertension (EH), and study their relationship. Methods:Using Holter and ambulatory blood pressure at the same time monitored 157 EH patients’ BPV and HRV in 24 hours as well as compared with 167 normotensions. Results: In the group that the rhythm of BP was disappeared (no-dipper), its parameters of BPV and HRV were abnormal, and its ECG abnormality was higher than other groups. In the group that there was the rhythm of BP (dipper), its parameters of HRV were nearly normal, its ECG abnormality was lower. There was significant relation between HRV and BP loading, HRV and ECG abnormality. Conclusion: The purpose of hypertensive treatment is not only to cut down BP, but also recover the rhythm of BP, to reduce BP loading, and to adjust autonomic nervous system function in order to decrease the damage of target organ.
出处
《昆明医学院学报》
2004年第4期83-86,共4页
Journal of Kunming Medical College
