期刊文献+

麻醉剂和泪膜对健康人角膜厚度的影响 被引量:16

The effects of topical anesthesia and tear film on pachymetry measurements
下载PDF
导出
摘要 目的 :探讨影响Orbscan角膜测厚准确性的各种因素 ,以期提高Orbscan测量精度。方法 :分别用Orbscan和A超测厚仪测量 6 3例正常志愿者 (12 6只眼 )的角膜中央厚度 (CCT) (角膜光学中心点厚度 )。正常志愿者本身情况做对照组。然后改变实验条件测量正常志愿者 ,得到以下几组 :①表麻剂组 (TA group) :双眼点表面麻醉剂后 1min、5min、10min、15min、2 0min、2 5min和 30min后 ,用Orbscan测量CCT ,重复三次 ,取均值。②角膜前泪膜组 (PTF group) :分收稿日期 :2 0 0 4-0 2 -0 8;修回日期 :2 0 0 4-0 4-2 5基金项目 :内蒙古医学院研究生基金课题 (2 0 0 10 77)。作者简介 :李坤 (1972 -) ,男 ,山东东营人 ,医学硕士 ,研究方向 :临床视光学和青光眼。E -mail:LK112 5cn @hotmail.comA、B两组。点表麻剂 1min后用无菌吸水海绵签移除角膜前泪膜后 (A组 )以及用无菌玻璃棒刺激结膜产生反应性流泪(B组 )后 10s、10min、2 0min和 30min时 ,用Orbscan和A超测量CCT ,各重复三次 ,取均值。结果 :用Orbscan和A超测厚仪测得正常志愿者平均CCT分别为 (5 39.3± 4 0 .7) μm和(5 4 7.3± 38.6 ) μm。点表麻剂后中央角膜厚度较正常对照组增加 ,且随时间呈抛物线性关系。 Objective:To investigate factors affecting the accuracy of Orbscan pachymetry measurements(OP),with the anticipation of improving the precision of OP.Methods:In 126 eyes of 63 normal volunteers,CCT(central cornea thickness) was measured using both OP and UP(ultrasonic pachymetry measurements). The results from normal volunteers were used as the control group. The subjects were then divided into three groups:①Topical anesthesia(TA) group:after applying an anesthetic to the cornea,CCT was consecutively measured at 1 minute,5 minutes-10 minutes,15 minutes,20 minutes,25 minutes and 30 minutes by OP and UP.②Pre corneal tear film(PTF) group:divided into A and B sub groups. After experimentally removing(A sub group) and using a sterile glass stick to stimulate the conjunctiva of the volunteers,CCT was measured by ORB and ultrasound A,respectively,at 10 seconds,10 minutes,20 minutes and 30 minutes. All results were statistically analyzed.Results:The mean CCT in the control group measured by OP and UP was (539.27±40.71)μm and (547.33±38.60)μm,respectively(P<0.05). Compared to the control group,the mean CCT of the TA group increased and displayed a throw liner over time(P<0.05). The difference in the mean CCT measured by OP before and after removing PTF was smaller than the difference in the mean CCT measured by UP(P<0.05). After the reactive tears were created,the mean CCT had obviously increased compared to that of the control group(P<0.05).Conclusion:CCT increased reversibly after being anesthetized and displayed a throw liner over time. When CCT is measured by OP,the PTF needs to be included in the assessment. [
出处 《眼视光学杂志》 2004年第4期244-246,共3页 Chinese Journal of Optometry & Ophthalmology
基金 内蒙古医学院研究生基金课题 (2 0 0 10 77)。
关键词 泪膜 正常 CCT 角膜厚度 表麻 A超 对照组 志愿者 抛物线 结论 pachymetry measurement tear film topical anesthesia
  • 相关文献

参考文献9

  • 1Yaylali V,Kaufman SC,Thompsom HW. Corneal thickness measurements with the Orbscan Topography System and Ultrasound Pachymetry[J]. J Cataract Refract Surg,1997,23(9):1345-1350.
  • 2李凤鸣.眼科全书(上册)[M].北京:人民卫生出版社,1997.42.
  • 3谢立信,李赵霞,胡隆基,衣伟伟.Orbscan-Ⅱ在准分子激光原位角膜磨镶术术前检查中的应用[J].眼视光学杂志,2001,3(3):133-136. 被引量:13
  • 4Iskander NG,Anderson Penno E,Peter NT,et al. Accuracy of Orbscan pchymetry measurements and DGH ultrasound pachymetry in primary laser in situ Keratomileusis and LASIK enhancement procedures[J]. J Cataract Surg,2001,27(5):681-685.
  • 5Nissen J,Hjortdal JO,Ehlers N,et al. A clinical comparison of optical and ultrasonic pachymetry[J]. Acta Ophthalmol Copenh,1991,69(5):659-663.
  • 6Lattimore MR Jr. Influence of extended soft contact lens wear on the comparative measurenent of central corneal thickness[J]. Acta Ophthalmol Scand,1996,74(2):239-242.
  • 7Mertz GW. Overnight swelling of the living human cornea[J]. J Am Optom Assoc,1980,51(2):211-214.
  • 8Lattimore MR Jr,Sandor Kaupp MS,Schallhorn S,et al. Orbscan pachymetry:implication of a reperted measures and diurnal variation analysis[J]. Ophthalmology,1999,106(5):977-981.
  • 9Dursun D,Monroy D,Knighton R,et al. The effects of experimental tear film removed on corneal surface regularity and barrier function[J]. Ophthalmology,2002,107(9):1754-1760.

二级参考文献3

  • 1Liu Zuguo,Br J Ophthalmol,1999年,83卷,774页
  • 2Wang Z,Ophthalmology,1999年,106卷,2期,406页
  • 3孙秉基,角膜病的理论基础与临床,1994年,184页

共引文献15

同被引文献126

引证文献16

二级引证文献68

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部