摘要
目的 观察还原型谷胱甘肽 (glutathion ,GSH)治疗稳定型心绞痛的疗效及安全性。 方法 对5 6例稳定型心绞痛患者使用GSH 1 2 g/d治疗 ,疗程 2周 ;对照组 5 6例使用 10 %GS 5 0 0ml+RI 12U +10 %kCL 10ml(G I K液 ) /d治疗 ,疗程 2周。治疗前后观察患者心绞痛发作次数 ,硝酸甘油消耗量及心电图、心肌耗氧指数等变化情况并进行对照分析。结果 GSH缓解心绞痛总有效率为 83 9% ,心电图改善总有效率为 5 3 6 % ,硝酸甘油消耗量及心肌耗氧指数明显下降 ,均较对照组优 ,差异显著 (P <0 0 5 )。结论 GSH治疗稳定型心绞痛疗效确切。
Objective To explore effects and safety of GSH therapy for stable angina pectoris.Methods 56 cases stable angina pectoris accepted GSH therapy(1.2g/d) for 2 weeks,another 56 cases as contrast group accepted G I K for 2 weeks.The relief of angina pectoris,electrocardiagram(ECG),nitrogloycerin consumption and myocardial oxygen consumption index were observed and contrasted between the two groups during therapeutical period.Results The effective rate of stable angina pectoris was 83.9%,the effective rate of ECG improvement was 53.6%,nitrogloycerin consumption and the myocardial oxygen cousumption index was dropped significuntly.All these indexes were significantly different from that of the contrast group.Conclusion GSH was a effective drug for stable angina pectoris.
出处
《中国基层医药》
CAS
2004年第12期1416-1418,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
还原型谷胱甘肽
治疗
稳定型心绞痛
临床研究
Glutathion
Stable angina pectoris
Eletrocardiography
Myocardial oxygen cousumption index
