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单纯疱疹病毒Ⅱ型与白血病的相关性研究

STUDY FOR CORRELATIVITY BET WEEN HSV-2
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摘要 小鼠白血病可由C型病毒引起早已得到证实。在本实验中用C型病毒接种小鼠以后其白血病的发生率是41.02%,用HSV—2(333)接种的小鼠以及对照组的小鼠均未发生白血病。当用了C型病毒与HSV—2(333)共同接种小鼠以后其白血病的发病率高达79.16%。它与单独接种了C型病毒的小鼠白血病发病率相比较,在统计学上具有高度显著性差异(P<0.01)。实验结果表明HSV—2(333)对小鼠无致白血病作用,可是它对C型病毒诱发小鼠白血病具有促进作用。 It has been early demonstrated that type C virus can induce murine leukemia. In this ex- periment, incidence of leukemia in them was 41. 02 per cent after mice were inoculated with type C virus, and both mice inoculated with HSV--2 (333) and the controls did not develop leukemia. Incidence of leukemia of mice, which were inoculated with HSV-2(333) plus type C virus,was up to 79. 16 per cent. When this rate compared to that of mice inoculated With type C virus alone, there was highly significant difference statistically (P<0. 01). The exper- imental result showed that HSV--2 (333) had not leukemogenic effect on mice,but it could promote type C virus to induce leukemia in mice.
出处 《山西白血病》 1993年第1期6-8,共3页
关键词 白血病 单纯疱疹病毒 HSV-2 type C virus leukemia
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参考文献3

  • 1刘建军,陈敏诲,杨占秋,胡珍姣,钱奇珍.人类HSV-2对小鼠白血病病毒诱发小鼠白血病的促进作用[J].湖北医学院学报,1991,12(1):17-24. 被引量:1
  • 2刘建军,陈敏诲,张蔚英.单纯疱疹病毒Ⅱ型与白血病病毒协同诱发小鼠淋巴细胞白血病的初步观察[J]湖北医学院学报,1985(01).
  • 3F. Rapp,Nancy Turner. Biochemical transformation of mouse cells by herpes simplex virus types 1 and 2: Comparison of different methods for inactivation of viruses[J] 1978,Archives of Virology(1-2):77~87

二级参考文献4

  • 1刘建军,陈敏诲,张蔚英.单纯疱疹病毒Ⅱ型与白血病病毒协同诱发小鼠淋巴细胞白血病的初步观察[J]湖北医学院学报,1985(01).
  • 2赏诗樟.单纯疱疹病毒Ⅱ型紫外线照射后的生物学特性[J]微生物学报,1983(04).
  • 3陈敏诲,孙瑜,张友新,张蔚英.重复感染疱疹二型病毒吴株诱发小白鼠宫颈癌的实验研究[J]实验生物学报,1980(03).
  • 4F. Rapp,Nancy Turner. Biochemical transformation of mouse cells by herpes simplex virus types 1 and 2: Comparison of different methods for inactivation of viruses[J] 1978,Archives of Virology(1-2):77~87

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