摘要
目的 了解福赛斯拟杆菌在慢性根尖周炎患牙根管内定植情况 ,探讨该菌与慢性根尖周炎临床症状间的关系。方法 收集 38例慢性根尖周炎患牙根管标本 ,采用 16 S r DNA PCR方法检测福赛斯拟杆菌在根管内分布情况 ,单因素相关分析福赛斯拟杆菌在根管内定植与慢性根尖周炎疼痛、叩痛、瘘道和肿胀间关系。结果 福赛斯拟杆菌在 38例慢性根尖周炎根管内检出 10例 ,检出率为 2 6 .3% ,与慢性根尖周炎的急性发作临床症状疼痛、叩痛、肿胀呈正相关关系 (OR分别为∞、9.0、12 .0 ) ,有统计学意义 (P<0 .0 5 ) ,与瘘道不存在相关关系 (OR=1.33)。结论 福赛斯拟杆菌能定植于根管内 。
Objective To investigate the distribution of Bacteroides forsythus in root canals with chronic apical periodontitis and to determine its associations with clinical symptoms. Methods Thirty- eight tooth root canals from 31 subjects were studied with a 16S rDNA-directed polymerase chain reaction (PCR). These teeth were classified into symptomatic and asymptomatic groups according to the clinical symptoms and signs, including spontaneous pain, percussion pain, sinus tract and swelling, respectively. Results Ten of the 38 root canal samples were positive for B. forsythus. The prevalence of B. forsythus was 26.3% for 38 root canals, 45.5% for spontaneous pain group, 39.1% for percussion pain group, 29.4% for sinus tract group, 42.9% for swelling group, respectively. Significant positive associations were observed between B. forsythus in infected root canals and the spontaneous pain, percussion pain, and swelling of apical periodontitis, respectively (OR=∞, 9,12; P<0.05). There was no significant association between B. forsythus and sinus tract of apical periodontitis (OR=1 33). Conclusion B. forsythus colonized in the infected root canals. It is the putative pathogen of apical periodontitis.
出处
《四川大学学报（医学版）》
CAS
CSCD
北大核心
2005年第1期46-49,共4页
Journal of Sichuan University(Medical Sciences)
基金
国家自然科学基金 (批准号 3 0 171175 )资助
关键词
福赛斯拟杆菌
感染根管
慢性根尖周炎
PCR
Bacteroides forsythus Infected root canal Chronic apical periodontitis PCR
