摘要
目的总结Vogt-K oyanagi -Harada(V K H )综合征患者的神经系统损害表现，探讨有诊断价值的辅助检查方法。方法对13 例患者的临床资料、脑脊液、影像学和电生理检查结果进行回顾性分析。结果11 例患者出现头痛，其中2 例为首发症状；10 例脑脊液检查结果全部异常（100%）；除常规检查外，5 例行病毒系列检查中1 例EBV-Ig M 阳性；8 例寡克隆区带（OB）检查5 例阳性；5 例髓鞘碱性蛋白(M B P )检查，1 例增高；9 例免疫球蛋白(Ig G )检查，4例增高；IgG24h合成率升高1例头部MRI 示视神经异常信号；1例视觉诱发电位潜伏期延长。结论头痛为本病常见症状，但缺乏特异性；脑脊液、影像学检查尤其是免疫学和病毒学指标以及诱发电位检查是主要的诊断依据。
Objective To investigate the neurological features of Vogt-Koyanagi-Harada (VKH) syndrome. Methods The data of 13 patients with VKH syndrome were reviewed and analyzed. Results Headache was the most common neurological symptom while other symptom were quite common too. Besides cell count changes, immunological and virus study of cerebral spinal fluid showed abnormal in our study. Optic nerve lesion was found in 1 case. Conclusions Headache is the commonest symptom but is lack of specificity. Lumbar puncture examine and head imaging are helpful to the early diagnosis of VKH syndrome.
出处
《北京医学》
CAS
2005年第1期22-24,共3页
Beijing Medical Journal
