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近视LASIK术后屈光回退眼和非回退眼角膜形态改变的差异 被引量:13

Changes of cornea in regressive and non-regressive eyes after LASIK for myopia
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摘要  目的 比较近视LASIK术后屈光回退眼和非回退眼角膜形态改变的差异,并评价这种差异在近视回退中的可能作用机制。 方法 近视回退组 15眼;非回退组 21眼。运用OrbscanⅡ系统分别在LASIK术前,术后 1周、1个月和3个月测量两组的角膜前 /后表面曲率半径和中央角膜厚度。 结果 两组术后的中央角膜厚度值都随着随访时间而增长,术后 1周值显著低于术后 1个月(P=0 000)和术后 3个月值(P=0 000)。但两组术后角膜前后表面的变化过程不一致,回退组角膜后表面曲率半径保持相对稳定(P>0 05),而术后 3个月前表面曲率显著凸于 1周值 (P=0 002);非回退组角膜后表面随时间而变扁平(P<0 05),而前表面曲率半径保持相对稳定 (P>0 05)。 结论 LASIK术后全角膜向前膨隆可能是近视回退的主要因素。 Objective To compare the difference of biomechanical changes of cornea between regressive eyes and non regressive eyes after myopic LASIK,and evaluate the possible roles of these changes on refractive regression following surgery. Methods Central corneal thickness (CCT) and anterior/posterior corneal curvature radiuses(CCR)were measured in 15 regression eyes and 21 non regression eyes by scanning slit topography before LASIK and postoperative 1week,1month and 3months. Results The CCT was increased with the prolong of follow up time in both non regressive eyes and regressive eyes.The posterior CCR was relatively stable,and the anterior CCR at the 3rd month was significantly decreased in comparison with that of week 1 ( P =0 002) after LASIK in the regression group.However,in the non regression group,the postoperative posterior CCR was significantly increased with time,and there was insignificant change in anterior CCR after LASIK. Conclusion The refractive regression after LASIK is mainly attributed to pan corneal protrusion rather than central corneal thickening.
作者 潘青 顾扬顺
出处 《眼科研究》 CSCD 北大核心 2005年第1期86-88,共3页 Chinese Ophthalmic Research
关键词 角膜 准分子激光原位角膜磨镶术 近视眼 屈光回退 cornea LASIK myopia refractive regression
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