期刊文献+

胰腺癌1027例临床流行病学研究 被引量:6

Clinical epidemiological research on pancreatic cancer:an analysis of 1027 cases
下载PDF
导出
摘要 目的:研究胰腺癌的病因因素及临床特征. 方法:计算比数比和95%可信区间或经T检验来估计生活饮食习惯、血型、外科手术史、生育史、疾病及家属史、实验室检查对胰腺癌的危险性. 结果:某些饮食习惯如吸烟、喝酒(P<0.01)、血型(男性A、B型,P<0.05)、外科手术史(阑尾切除术、部分胃切除术、胆囊切除术等,P<0.01)、生育史、疾病(糖尿病、结石症等)、家属史及实验室检查(HB,ALB, AKP,GGT,GLU)与胰腺癌相关. 结论:戒烟,不酗酒,控制身体质量,不行胃、胆囊、阑尾手术,女性适龄少生可减少胰腺癌的发生,对于胰腺癌相关因素伴相关临床特征者应常规行胰腺检查并随访. AIM: To study the pathogenic factors and clinical features of Pancreatic cancer (PC). METHODS: The odds ratio (OR) and its 95% confidential interval (Cl) were calculated.t-test was used to evaluate the risks of life and diet habits, ABO blood types, surgical history, reproductive history, medical conditions and familial history as well as laboratory tests in the induction of PC. RESULTS: Some life and diet habits such as smoking and drinking (P<0.01), ABO blood types (type A and B in males, P<0.05), surgical history such as appendectomy, Partial gastrectomy, and cholecystectomy (P<0.01), reproductive history, medical diseases (diabetes, etc.), familial history, laboratory tests (HB, ALB, AKP, GGT, GLU) were associated with PC. CONCLUSION: In order to reduce the occurrence of PC, it is helpful to stop smoking and alcohol drinking, to control body weight, to avoid appendectomy, partial gastrectomy and cholecystectomy, to reduce childbearing at proper age for females. Routine examination for pancreas and follow-up should be taken for those patients who have the related factors and clinical features of PC.
出处 《世界华人消化杂志》 CAS 北大核心 2005年第1期55-60,共6页 World Chinese Journal of Digestology
基金 "10.5"全军医学重大技术项目资助课题
  • 相关文献

参考文献26

  • 1徐选福,王兴鹏.胰腺癌诊断学新认识[J].世界华人消化杂志,2000,8(9):1034-1036. 被引量:6
  • 2刘民培,马景云,潘伯荣,马连生.中国胰腺癌的研究[J].世界华人消化杂志,2001,9(10):1103-1109. 被引量:14
  • 3Lowenfels AB, Maisonneuve P. Epidemiology and prevention of pancreatic cancer. Jpn J Clin Oncol 2004;34:238-244.
  • 4Lowenfels AB, Maisonneuve P. Epidemiologic and etiologic factors of pancreatic cancer. Hematol Oncol Clin North Am 2002;16:1-16.
  • 5Alguacil J, Silverman DT. Smokeless and other noncigarette tobacco use and pancreatic cancer:a case-control study based on direct interviews. Cancer Epidemiol Biomarkers Prey 2004;13:55-58.
  • 6Villeneuve PJ, Johnson KC, Mao Y, Hanley AJ. Environmental tobacco smoke and the risk of pancreatic cancer: findings from a Canadian population-based case-control study. Can J Public Health 2004;95:32-37.
  • 7Mulder I, Hoogenveen RT, van Genugten ML, Lankisch PG,Lowenfels AB, de Hollander AE, Bueno deMesquita HB.Smoking cessation would substantially reduce the future incidence of pancreatic cancer in the European Union. Eur J Gastroenterol Hepatol 2002;14:1343-1353.
  • 8Ye W, Lagergren J, Weiderpass E, Nyren O, Adami HO, Ekbom A. Alcohol abuse and the risk of pancreatic cancer. Gut 2002;51:236-239.
  • 9Michaud DS, Giovannucci E, Willett WC, Colditz GA, Fuchs CS. Coffee and alcohol consumption and the risk of pancreatic cancer in two prospective United States cohorts. Cancer Epidemiol Biomarkers Prev 2001;10:429-437.
  • 10Berrington de Gonzalez A, Sweetland S, Spencer E. A metaanalysis of obesity and the risk of pancreatic cancer. Br J Cancer 2003;89:519-523.

二级参考文献115

共引文献17

同被引文献62

引证文献6

二级引证文献35

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部