摘要
目的观察中药胃炎胶囊对慢性萎缩性胃炎的治疗效果。方法应用胃炎胶囊(柴胡、白术、佛手、蒲公英等9味药组成)治疗慢性萎缩性胃炎患者100例。其中轻度萎缩性胃炎42例,中度38例,重度20例;伴肠腺化生41例,Ⅰ度不典型增生13例。男63例,女37例,年龄30～65岁,平均51±8岁,病程6～100个月,平均60.0±18.5个月。临床表现胃脘痛者86例,胃脘胀满72例,纳呆90例,嗳气34例,口苦20例。连用3个月后,对患者的临床症状、胃黏膜的改善情况进行比较分析。结果经胃炎胶囊治疗3个月,临床治愈7例,显效48例,有效34例,无效11例,愈显率55.0%,总有效率为89.0%。轻度萎缩性胃炎42例中有33例转为浅表性胃炎,4例恢复正常,5例无变化;中度萎缩性胃炎38例中17例转为轻度萎缩性胃炎,14例转为浅表性胃炎,3例恢复正常,4例无变化;重度萎缩性胃炎20例中10例转为中度萎缩性胃炎,8例转为浅表性胃炎,2例无变化。肠腺化生轻度26例中消失20例,无变化6例;中度8例,转为轻度化生4例,消失1例,3例无变化;重度7例中有2例转为中度,2例转为轻度化生,3例无变化。Ⅰ度不典型增生13例中有7例恢复正常,6例无变化。结论胃炎胶囊对慢性萎缩性胃炎有良好的治疗作用,对气滞型和虚寒型疗效相同。
Objective To study the therapectic effect of Chinese herbs gastritiscapsule on chronic atrophic gastritis.Methods One-hundred patients with chronic atrophic gastritis were treated with gastritis capsule.Of them,42(42%) were mild,38(38%) moderate and 20 (20%) sever atrophic gastritis and 41(41%) and 13 (13%) accompanied with intestinal metaplasia (IM) and I degree dysplasia (Dys),respectively .Of the 100 patients, 63 were men and 37 were wonen,aged30-65 years,and the mean age was 51 8 years.The clinical manifestations were stomach duck pain (86 patients),fulless of abdonen (72),anorexia (90) ,eructation (34),bitterness of the mouth (20) .After treatment for three months the inprovement of patients symptoms, atrophy of gastric mucosa ,IM and Dys were analysed. Results After 3 months with gastritis capsule, 7 atients were recovered, 48 very effective,34 improvedd,and 11 inflective.the total efficacy was 89% with 4 normality ,and 5no change.Of the 38 patients with moderate atrophic gasteitis,17becane mild atrophic gastritis,14 superhic gasteitos,3 normality and 4 no changes.Of the20 severe atrophic gasteitis ,10turned into moderate atrophic gasteitos ,8 superficial gastritis and 2 had no changes.Of the 26 patients with mild IM, IM disappeared in 20 ,and 6 had no changes.Of the 8 patients with moderate IM, IM disappeared in 1,4 changed into mild IM,and 3 had no changes .Of the 7 aptients with sever IM,2 changed into mderate IM,2 mild IM, and 3 had no changes.Of the 13 patients with I degree Dys ,Dys disappeared in 7,and 6 had no changes.Conclusion Gastritis capsule has better therapeutic effects on choric atrophic gastritis.
出处
《基层医学论坛》
2005年第1期7-8,共2页
The Medical Forum
