摘要
目的 探讨彩超在原发性肝癌介入治疗前后的临床应用价值 ,评价TACE、TACE +PLI的治疗效果。方法 所有病例于治疗前1天、治疗后 1周、2周以及治疗后每月行一次超声检查 ,同时定期行血清AFP测定 ,再手术病例及治疗后穿刺取活检病例可用病理结果来判断治疗效果。结果 两组治疗前后AFP、肿瘤直径、肿瘤血供、肝固有动脉峰值速度、RI均有显著变化 (P <0 0 5 ) ,TACE +PLI组较TACE组AFP转阴率升高 (P <0 0 5 )、肿瘤直径缩小、肿瘤血供减少、肝固有动脉内径减小、峰值速度减慢 (P <0 0 5 ) ,RI升高 (P <0 0 5 )。结论 彩超为判断肝癌的治疗效果提供了一种简便、及时、准确的方法 ,对治疗方法的选择、治疗方案的确定和预后评估亦具有重要意义。TACE、TACE +PLI在肝癌的治疗中有较好的疗效 ,TACE
Objective To study the clinical value of color Doppler ultrasonography and therapeutic effect of TACE and TACE+PLI in primary hepatic carcinoma before and after interventional therapy. Methods All cases were examined by CDU one day before, one week after, two weeks after and every month after therapy. We determined AFP at the same time, judged the therapeutic effect by pathological effect after re-operation and biopsy. We judged the long-term therapeutic effect by follow-up survival rate. Results There were two groups after therapy:AFP, the diameter of tumor, the blood supply of tumor, the υ max of proper hepatic artery and RI of proper hepatic artery had obvious difference (P<0.05). The rates of AFP turned from positive to negative and RI of group TACE+PLI were more increased than that of group TACE (P<0.05),and the diameter of tumor, the blood supply of tumor, the diameter and the υ max of proper hepatic artery were decreased (P<0.05). Conclusion CDU was a simple, prompt, accurate method to judge the therapeutic effect and had very important significance to select the therapeutic method and to evaluate the prognosis.
出处
《河南肿瘤学杂志》
2005年第1期36-39,共4页
Henan Journal of Oncology
关键词
彩色多普勒超声
肝细胞肝癌
介入治疗
color Doppler ultrasonography
hepatic carcinoma
interventional therapy