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2例Melkersson-Rosenthal综合征患者免疫状态的检测 被引量:1

Investigation on the Immune Status of Two Patients with the Melkersson-Rosenthal Syndrome(MRS)
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摘要 目的 :总结分析两例Melkersson Rosenthal(MRS)综合征患者的临床表现、组织病理和治疗转归 ,探讨其可能的免疫学发病机制。方法 :对 2例MRS患者的外周血IL 2、IFN γ、IL 4、IL 1 0水平应用ELISA方法作检测。结果 :2例MRS患者外周血Th1型血细胞因子IL 2、IFN γ水平明显低于正常对照组 ,Th2型细胞因子LI 4、IL 1 0水平和正常对照组相比增高。结论 :Th1 /Th2细胞动态平衡打破 。 Objective:We analysed the clinical presentation, clinicopathologic features, and mangagement of two patients with MRS, and explore the possible pathogenesis of MRS.Methods:The serum levels of Th1 and Th2 cytokines were detected by enzyme-linked immunosorbent assay in 2 patients with MRS and 2 normal controls. Results:The levels of Th1 cytokinges IL-2,IFN-γ in peripheral blood were significantly lower in patients with MRS than those in controls respectively. There was no statistical difference in the level of IL-4,IL-10 in peripheral blood between the patients and controls.Conclusion:The imbalance of Th1/Th2 might be one of the pathogenesis of MRS.
出处 《岭南皮肤性病科杂志》 2004年第4期322-324,334,共4页 Southern China Journal of Dermato-Venereology
关键词 MELKERSSON-ROSENTHAL综合征 细胞因子 TH1/TH2细胞平衡 Melkersson-Rosenthal syndrome cytokine the balance of Th1/Th2
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参考文献3

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同被引文献13

  • 1栗偲平,李瑾娴,刘巨川,李久宏,宋芳吉.Melkersson—Rosenthal综合征一例[J].国际皮肤性病学杂志,2007,33(2):71-71. 被引量:1
  • 2李瑞平,吴建新.梅一罗综合征(附2例报告)[J].实用口腔医学杂志,2001,17(1):36.
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  • 7Baeci C, Valente ML. Successful treatment of cheilitis granulomatosa with intralesional injection of triamcinolone [J]. J Eur Acad Dermatol Venereol,2010,24- (3) :363-364.
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