摘要
综述近年针灸在实验性糖尿病和其他内分泌代谢相关性疾病 (EMAD)中应用的研究进展。资料表明 ,针灸可用于治疗糖尿病和糖尿病慢性并发症 (血管、神经、视网膜病变等 ) ,以及改善Ⅱ型糖尿病及EMAD的胰岛素抵抗 (IR)作用 ;并对针刺的治疗作用进行了作用机制的探讨。
In the present paper, the authors review recent pr ogresses of acu-moxibustion tr eatment of experimental diabetes mellitus(DM)and insulin resistance(IR)of ty pe Ⅱ(TⅡ)DM and other endocrinous metabolism-associated diseases (EMAD )from 1) study on the effect of acu-moxibustion on experimental DM and its chronic comp li cations(diabetic vascular pathological change, nervous lesion and retinopathy) and mechanisms, and 2) study on the effect of acu-moxibustion on insulin growth fact or-1 receptor (IGF-1R) in TⅡDM and EMAD animals. In addition, the authors p ut f orward some existent problems in the research on DM, IR and EMAD, such as ① the generally acknowledged effective acupoints; acupuncture induced effect or stres s reaction, ② needling maneuvers, needle retention duration and stimulation int ensities, ③ systematic study on the effect of the metabolism of glucose and fa t, glycosylation-oxydation stress, aldose-reductase activity on the occurrenc e a nd development of the complications of DM, the interaction among hormones, and i ts relation to nerve-endocrine-immune network, ④ different levels of resea rche s including wholism, cytology and molecular biology, ⑤ the acting target site o f acupuncture, ⑥ indexes and evaluating methods for IR, ⑦ the effect of fre e fatty acid on IR, and ⑧ new trains of thought for improving IR.
出处
《针刺研究》
CAS
CSCD
2004年第4期299-303,309,共6页
Acupuncture Research
基金
广东省中医药局滚动资助项目 (30 2 0 0 3)
广州市中医药
中西医结合课题资助项目 (2 0 0 2 37)
关键词
针灸
实验性糖尿病
糖尿病并发症
胰岛素抵抗
针刺治疗
Experimental diabetes mellitus Diabetic complications Insulin resistance Acupuncture therapy
