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用脉冲放电产生救治呼吸衰竭用一氧化氮的研究 被引量:10

STUDY ON PRODUCTION OF NITRIC MONOXIDE FOR RESPIRATORY DISTRESS BY PULSED DISCHARGE
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摘要 NO近年被作为救治急性呼吸衰竭综合征(ARDS)的新方法而受到重视。文中采用多针-板电极、负脉冲放电装置,以大气压下的干燥空气为原料,产生临床治疗所需要的NO。研究了包括脉冲放电电流、电极间的距离、干燥空气的流量、放电时间和加热温度等一些参数对NO和NO2浓度的影响。结果发现:放电电流对NO和NO2的浓度有显著影响,NO、NO2浓度和NO2/(NO+NO2)的值,随放电时间的延长和气体流量的增加而降低。放电过程中产生的少量NO2有害气体,可以通过加热的金属钼丝还原转化为治疗需要的NO。该实验装置产生的NO和NO2浓度完全可以满足目前医疗救治的要求。 As a new approach to treat acute respiratory distress syndrome (ARDS), NO has recently received more attention. In the present work, NO is generated by negative pulsed discharge equipment between multi-rod and plate electrodes in dry air at the atmospheric pressure. Some of the important parameters affecting concentration of NO and NO2 have been investigated. These include the pulsed discharge current, the distance between electrodes, the flow rate of dry air, the duration of discharge and heated temperature. The results show that power supply voltage considerably affects the concentration of NO and NO2. The concentration of NO and NO2 and the ratio of NO2/(NO+NO2) decreases with extending discharge and increasing flow rate. A small quantity of NO2, which is known to be a toxic gas, can be deoxidized to NO using a heated molybdenum wire. The resulting concentration of NO and NO2 in the experiment is completely fit for medical treatment
机构地区 华中科技大学
出处 《中国电机工程学报》 EI CSCD 北大核心 2005年第2期98-102,共5页 Proceedings of the CSEE
基金 国家自然科学基金项目(50347009)
关键词 呼吸衰竭综合征 脉冲放电 一氧化氮 脉冲发生器 临床治疗 High voltage engineering Pulse discharge Inhaled Nitric Oxide Molybdenum Acute respiratory distress syndrome
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