摘要
目的视网膜静脉周围炎的细胞学研究目的在于探讨其发病原因、发展过程及其在病理细胞学方面的机制，为寻求行之有效的治疗方法提供组织学依据。方法临床确诊为视网膜静脉周围炎，玻璃体出血伴增生性玻璃体视网膜病变或继发视网膜脱离者４５例（４８只眼）。结果玻璃体取出物细胞例数为淋巴细胞和成纤维细胞占首位。免疫组化染色及电镜证实检出的淋巴细胞中Ｔ淋巴细胞分别占７８．８％和６１．５％。结论视网膜静脉周围炎引起的增生性玻璃体视网膜病变与Ｔ淋巴细胞密切相关，提示自身免疫反应在发病机理中可能起了一定作用。
Objective To study the pathcytological mechanism of Eales disease and to provide a histological testimony for an effictive therapy. Methods 45 cases(48 eyes) of Eales disease that were diagnosed according to vitreous hemorrhage and proliferative vitreoretinopathy or secondary retinal detachment. Cytomorphological examination was taken and vitreous extracts were examined by immunohistochemical staining. Result Lymphocytes and fibroblastes were most of those cells in the vitreous extracts. Immunohistology and electron microscopy revealed that lymphocytes were 78. 8% or 61. 5% in all specimens, respectively. Conclusion Proliferative vitreoretinopathy induced by Eales disease closely relates with lymphocytes. The results suggested that autoimmunity might play an important role in the pathogenic mechanism of the disease.
出处
《眼科研究》
CSCD
北大核心
2001年第3期217-219,共3页
Chinese Ophthalmic Research
