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脑胶质瘤促红细胞生成素的表达及其生物学意义 被引量：5

Biological significance of erythropoietin expression in human gliomas
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摘要 目的　探讨人脑胶质瘤中促红细胞生成素 (erythropoietin,EPO)的表达 ,并研究其与肿瘤病理分级、Ki- 6 7、CD10 5的关系。方法　采用免疫组化 S- P法 ,检测 4 9例人脑胶质瘤中 EPO、Ki- 6 7、CD10 5的表达。结果　EPO的表达与肿瘤病理分级有关 (χ2 =15 .19,P<0 .0 1) ;与 Ki- 6 7、CD10 5的表达密切相关 (F 分别为 19.4 5、16 .4 2 ,P值均 <0 .0 1)。结论　 EPO的表达可作为判断脑胶质瘤恶性程度的一个重要指标。EPO能促进肿瘤细胞增殖和血管形成 ,促进肿瘤生长。
作者 刘志忠 张宇新 阚志生 丁秀荣 秦玉霞 张惠卿
机构地区 华北煤炭医学院 华北煤炭医学院人体解剖学教研室 华北煤炭医学院附属开滦医院神经外科
出处 《实用肿瘤杂志》 CAS 2005年第1期43-45,共3页 Journal of Practical Oncology
关键词 神经胶质瘤 促红细胞生成素 KI-67 CD105 免疫组织化学
分类号 R739.4 [医药卫生—肿瘤]
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参考文献11

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同被引文献59

  • 1刘志忠,阚志生,张宇新,丁秀荣,秦玉霞.脑胶质瘤CD105的表达与临床病理、及促红细胞生成素的关系[J].现代肿瘤医学,2005,13(2):202-204. 被引量：1
  • 2黄志勇,谭志明.血清TNF-α、IL-6和EPO检测在类风湿性关节炎伴贫血患者中的意义[J].实用医学杂志,2005,21(15):1640-1641. 被引量：4
  • 3王俊英,牛敬忠,胡冬梅.急性脑出血患者血清中促红细胞生成素含量研究[J].泰山医学院学报,2006,27(5):416-417. 被引量：3
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实用肿瘤杂志
2005年 第1期

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