摘要
目的探讨高血压患者尿中微量蛋白早期检测的临床意义及应用苯那普利进行治疗的必要性。方法分别测定60例高血压(工期)患者应用苯那普利治疗前后(高血压组)及30例健康体检者(对照组)尿中α1-微球蛋白(α1-MG)、β2-微球蛋白(β2-MG)及白蛋白(心)含量,分析高血压患者经苯那普利治疗后,尿中上述物质含量的变化。结果高血压组患者经苯那普利治疗8周后α1-MG、β2-MG及Alb含量均有下降,与治疗前比较具有明显差异性(P<0.05),与对照组比较无差异性。结论早期应用苯那普利类药物治疗高血压病,对肾功能具有明显的保护作用。
Objective To study the significance of early-stage examination of trace protein in urine of patients with hypertension and the necessity of treatment with Benazepril.Methods The contents of α 1-MG, β 2-MG and AIb in urine of 60 cases with hypertension(I stage ) treated with Benazepril before and after treatment and 30 healthy persons(the control group) were detected,then the change in the contents above in urine would be analysed after treatment with Benazepril.Results In the hypertension group,t...
出处
《第四军医大学吉林军医学院学报(86813X)》
2002年第2期77-79,共3页
Journal of Jilin Military Medical College Fourth Military Medical University