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异丙酚联合芬太尼麻醉用于结肠镜检查的临床观察 被引量:18

Clinical study on the effect of propofol combined with fentanyl to colonoscopy
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摘要 目的观察异丙酚联合芬太尼应用于结肠镜检查的麻醉效果。方法选择100例行结肠镜检查的病人,随机分为PF组(异丙酚+芬太尼n=50)和P组(异丙酚n=50)。PF组在镜检前静注芬太尼1 μg/kg、异丙酚1 mg/kg, 异丙酚30 ml/h静脉泵注;P组镜检前异丙酚1.5 mg/kg静脉注射,异丙酚30 ml/h静脉泵注。直到患者进入浅睡眠状态,睫毛反射消失后,开始进行肠镜检查。检查时均予以吸氧。结果PF组镇痛效果优于P组(P<0.05),BP、HR、SpO2、操作时间、苏醒时间、离院时间及不良反应两组相比差异无显著性。结论异丙酚联合芬太尼麻醉技术,起效快、镇痛完善、苏醒迅速、不良反应较少,可安全有效地应用于结肠镜检查中。 Objective: To study the effect of propofol combined with fentanyl to colonoscopy. Methods: A hundred patients were randomly divided into Group PF (intravenous infusion of propofol and fentanyl n=50) and Group P (intravenous infusion of propofol n=50). Group PF with fentanyl 1 μg /kg iv plus propofol 1mg/kg iv before the procedure, propofol 30 ml/h iv continuously; Group P with 1.5 mg/kg iv before the procedure, propofol 30 ml/h iv continually. Blood pressure (BP), heart rate (HR), pulse oxygen saturation (SPO2), operative time, palinesthesia time, off hospital time and adverse reaction were recorded and analysed. Results: Analgesic effect in Group PF were better than in Group P (P<0.05). There was no notable difference between these two group in BP, HR, SPO2, operative time, palinesthesia time, off hospital time and adverse reaction. Conclusion: Anesthesia technology of propofol combined with fentanyl can be used to colonoscopy safely and effectively.
出处 《中国内镜杂志》 CSCD 2004年第12期61-62,共2页 China Journal of Endoscopy
关键词 异丙酚 芬太尼 静脉麻醉 结肠镜检查 propofol fentanyl intravenous anesthesia colonoscopy
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