摘要
为了观察自身免疫溶血性贫血 (AIHA)患者的同种抗体 ,用氯奎放散试验检测自身抗体掩盖的同种抗体 ,用乙醚放散试验检测自身抗体的特异性。结果表明 :3 8例AIHA病人中 ,间抗阳性者 19例 ,其中含同种抗体者 7例 (抗 D 1例 ,抗 E 4例 ,抗 CE 2例 ) ,自身抗体具有血型特异性者 5例 (抗 E 3例 ,抗 C 1例 ,抗 c 1例 )。结论 :采用氯奎放散试验、乙醚放散试验等检测被自身抗体掩盖的同种抗体 ,对AIHA患者的安全输血很重要。
To observe of alloantibodies of patients with autoimmune hemolytic anemia (AIHA), the alloantibodies masked by autoiantibody were detected by using chloroquine elution test, and the specificity of autoantibody was identified by ether elution test. The results showed that 19 cases out of 38 patients with AIHA were positive detected by indirect antiglobulin test and in 7 cases of them alloantibodies in sera cases were found (1 case of anti D, 4 cases of anti E and 2 cases of anti CE), in 5 cases of them alloantibody were detected carried blood group specificity (3 cases of anti E, anti C and anti c 1case repectively). In conclusion, detections of alloantibodies by chloroquine elution test and ether elution test were very important for transfusion safety in therapy of patients with AIHA.
出处
《中国实验血液学杂志》
CAS
CSCD
2004年第6期849-851,共3页
Journal of Experimental Hematology