摘要
目的探讨糖化血清蛋白(GSP)及糖化血红蛋白(HbAlc)在妊娠糖尿病诊断中的价值。方法对正常对照组50例,正常妊娠组50例及妊娠糖尿病组(GDM)36例等血清进行了空腹血糖(FPG)、口服葡萄糖50g筛选、GSP、HbAlc测定。结果GDM组FPG、糖筛选实验、GSP、HbA1c结果与正常妊娠组比较均明显增高,差异有显著性(P<0.05),在四项诊断妊娠糖尿病(GDM)检测中,以GSP的效果最为理想,其敏感性、特异性、可靠性、阳性预测分别为88.9%、98%、94.1%、96.9%,而HbA1c除敏感性比糖筛选实验稍低外,其它指标均高于FPG和糖筛选实验,其敏感性、特异性、可靠性、阳性预测分别为80.6%、96%、89.5%、93.5%。结论GSP与HbAlc检验方法快速、简单、实用、取血量少、不易受其它因素影响,可作为GDM诊断指标,其中又以GSP为首选。
Objective: To probe the value of the saccharification albumin and saccharification hemoglobin in diagnosing pregnancy diabetes. Methods: To measure serum carry on empty stomach blood sugar, oral glucose 50g screen, GSP and HbAlc for contrasting 50 cases in contrast group, normal gestation 50 of group and pregnancy diabetes 36 of group. Results: The results of FPG, GSP, glucose screen and HbAlc were significantly higher than those in normal gestation group obviously (P<0.05). The sensitivity, peculiar, dependability and predicting positively of four examination for diagnosing pregnancy diabetes were 88.9%, 98%, 94.1%, 96.9%. The most ideal one is GSP. sensitivity, peculiar, dependability and predicting positively of HbAlc were 80.6%, 96%, 89.5%, 93.5% respectively, which were higher than the FPG and glucose screen. Conculsion: GSP and HbAlc method of inspection are fast, simple, practical, the amount of blood fetched lacks, it is difficult to influence by other factors, can diagnose the index as GDM, among them it is first-selected with GSP.
出处
《中国医学工程》
2004年第6期87-88,91,共3页
China Medical Engineering
