摘要
目的 探讨全民食盐加碘后孕妇妊娠早期甲状腺功能及碘营养状况。方法 选择单纯食用合格碘盐补碘的 60名孕妇作为研究组 ,于妊娠 12～ 15周采集血、尿标本 ,化学发光免疫分析法测定血清FT3 、FT4和TSH水平 ,放射免疫分析法测定血清TMAb和TGAb水平 ,酸消化砷铈接触分光光度法测定尿碘水平 ,与 60名该地区非妊娠健康女性进行比较。结果 (1)研究组孕妇血清FT3 、FT4水平高于对照组 ,血TSH水平低于对照组 ,差异具有显著性 ;(2 )研究组孕妇血清TMAb和TGAb水平低于对照组 ,差异具有显著性 ;(3 )研究组孕妇尿碘中位数为 117.60 μg/L ,低于WHO推荐值。 结论全民食盐加碘后 ,孕妇甲状腺功能得到明显改善 ,但单纯食用碘盐不能满足孕妇任娠期生理需求 ,需要特别给予补充。
Objective To investigate the status of iodine nutritional status and thyroid function in the first trimester gestation after universal salt iodization.Methods The serum FT 3,FT 4,TSH,TMAb and TGAb levels of 60 pregnant women as the study group were tested with Chemiluminescent Immunoassay and Radioimmunoassay technique while the urine iodine levels were examined by Spectro photometry.The results were compared with those of the control group who were 60 non-pregnant women in the same area.Results ①The mean serum FT 3,FT 4 significantly higher than that of the control group;②The mean serum TMAb and TGAb significantly lower than that of the control group;③The median of urine iodine concentration in the study group was 117.60 μg/L,and lower than the level recommended by WHO.Conclusions After universal salt iodization,thyroid function of pregnant women are markedly improved,but iodine intakes daily from the qualified iodized salt can not satisfy the need of pregnancy,so they need special supplementation.
出处
《中国地方病防治》
北大核心
2005年第1期9-11,共3页
Chinese Journal of Control of Endemic Diseases
基金
山西省教委基金 (2 0 0 1 0 1 9)
