摘要
目的 探讨结肠癌局限性肝转移的治疗。方法 对 1987—2000 年收治的结肠癌根治术后局限性肝转移的81例临床资料进行回顾性研究。结果 原发癌加肝转移灶切除组 1、3、5 年生存率分别为85%、46%、32%,而肝转移灶未作局部治疗组的生存率分别为26%、0、0(P<0 05);联合应用肝转移灶微波固化和无水酒精注射及肝区域化疗组 1、3、5 年生存率分别为 74%、42%、19%,与肝转移灶切除组的差异无统计学意义(P>0 05)。结论 结肠癌局限性肝转移患者,应尽可能彻底切除原发癌和肝转移灶,肝转移灶微波固化和无水酒精注射及肝区域化疗是治疗措施的重要补充。
Objective To evaluate different treatment modaltities for limited (local) hepatic metastasis in patients of colonic carcinoma Methods We conducted a retrospective analysis on 81 cases of colonic cancer suffering from hepatic local metastasis from 1987 to 2000 Results The 1、3、5 year survival rate was 85%、 46% and 32% respectively for patients underwent resection of metastatic liver cancer, and 26%、 0 and 0, respectively for those not having the metastatic liver cancer resected ( P <0 05) The 1、 3、 5 year survival rate was 74%、 42% and 19%, respectively for patients, with the liver tumor treated by percutaneous ethanol injection (PEI) or microwave coagulation treatment (MCT) or/and intraarterial regional chemotherapy, which was comparable with that achieved by tumor resection ( P >0 05) Conclusion Resection or ablation therapy promises a much longer long term survival than do nothing in colonic cancer patients with local liver metastatic tumor
出处
《中华普通外科杂志》
CSCD
北大核心
2005年第2期102-103,共2页
Chinese Journal of General Surgery
