摘要
目的:探讨环氧合酶 2在雄性大鼠睾丸和附睾组织中的表达及其意义。 方法:应用免疫组化SP法检测 40只雄性SD大鼠睾丸和附睾组织中环氧合酶 2的表达及其定位情况。 结果:环氧合酶 2在雄性大鼠的睾丸和 附睾组织中有较强的表达。在附睾头部主要表达于腔上皮细胞的细胞核内,部分细胞质内也可见表达,睾丸精原 细胞胞质和细胞核内均可见棕黄色颗粒。 结论:免疫组化法可较为敏感地检测环氧合酶 2在雄性大鼠睾丸和 附睾组织的表达。
Objective: To investigate the expression of cyclooxygenase-2 (cox-2) in the testes and epididymides of adult male rats and its significance. Methods: Immunohistochemical staining was used to detect the expression and localization of cox-2 in the testicle and epididymal tissues of 40 adult male SD rats. Results: Strong cox-2 immunoreactivity was detected in the epididymides and testes of the rats. In the caput epididymides, cox-2 expressed mainly in the epithelial nuclei and partly in the cytoplasm. Cox-2 was also found positive in the testis nuclei and cytoplasm. Conclusion: Immunohistochemical staining is a fairly sensitive method for detecting cox-2 expression in the testes and epididymides of adult male rats.
出处
《中华男科学杂志》
CAS
CSCD
2005年第2期104-105,111,共3页
National Journal of Andrology
