期刊文献+

颞叶癫痫与学习、记忆障碍 被引量:2

下载PDF
导出
摘要 颞叶癫痫的发作与海马等边缘系统的病变密切相关 ,而海马等结构又参与了学习、记忆等认知功能的形成。最近有关颞叶癫痫发作后引起的学习、记忆功能障碍逐渐得到人们的认识和重视。学习记忆的神经生物学机制是十分复杂的 ,本文从学习、记忆的解剖基础、突触修饰理论、长时程增强、神经细胞内钙离子等方面 ,对颞叶癫痫发作后引起的学习记忆障碍的机制进行了综述。
出处 《立体定向和功能性神经外科杂志》 2005年第1期56-59,共4页 Chinese Journal of Stereotactic and Functional Neurosurgery
  • 相关文献

参考文献16

  • 1关汉明.医学神经生物学[M].北京:人民卫生出版社,2002.348-361.
  • 2Hannesson DK,Mohapel P,Coreoran ME. Dorsal hippocampal kindling selectively impairs spatial learning/short-term memory[J]. Hippocampus,2001,11 (3) :275 --286.
  • 3Janszky J ,Jokeit H, Heinemann D, et al. Epileptic activity influences the speech Organization in medial temporal lobe epilepsy[ J ]. Brain, 2003,126 : 2043 - 2051.
  • 4Kwan P, Brodie MJ. Neuropsychological effects of epilepsy and antiepileptic drugs[ J ]. Lancet, 2001,357 ( 9251 ) : 216-222.
  • 5Renaud J, Emond M, Meillcur S, et al. AIDA, a class I metabotropic glutamate-receptor antagonist limits kainiteinduced hippocampal dysfunction [ J ]. Epilepsia, 2002, 43(11) :1306- 1317.
  • 6Niikura Y. Abe K. Misawa M. Involvement of L-type Ca^(2+) channels in the induction of long-term potentiation in the basolateral amygdala-dentate gyms pathway of anesthetized rats[J].Brain Res,2004,1017(1-2):218-221.
  • 7Adams SV, Winterer J, Muller W. Muscarinic signaling is required for spike-pairing induction of long- term potentiation at rat Schaffer collateral-CA1 synapses[ J ]. Hippocampus,2004,14(4) :413 -416.
  • 8Mula M, Trimble MR, Sander J WAS. The role of hippocampal sclerosis in topiramate-related depression and cognitive deficits in people with epilepsy[J]. Epilepsia,2003.44(2) :1573 - 1577.
  • 9Beck H,Goussakov IV, Lie A, et al . Synaptic plasticity in the human dentate gyrus [J]. J Neurosci, 2000,20 (18) :7080-- 7086.
  • 10Kada T, Yamada N ,Tsuzuki K, et al. Long-term potention in the hippocampal CA1 area and dentate gyrus plays different roles in spatial learning[J]. Eur J Neurosci,2003,17(2):341 -349.

同被引文献21

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部