摘要
目的 研究银杏叶片抗燃煤型砷中毒肝纤维化作用。方法 选择燃煤型砷中毒高发区 84例慢性砷中毒患者 ,银杏叶片治疗 3月 ,对照组用安慰片。检查治疗前后患者血清PAF及四项肝纤维化指标 ,部分患者作治疗前后的病理学检查。结果 治疗组血清PAF及四项肝纤维化指标治疗后较治疗前有明显降低 (P <0 .0 1)。治疗组的显效率和总有效率分别为 4 5 .5 %和 79.5 % ,而对照组的显效率和总有效率分别是 17.5 %和 4 2 .5 % ,两者比较有显著性差异 (P <0 .0 1)。治疗组治疗后的肝脏病理有一定的改善。
Objective To study the anti-hepatic fibrosis effect of Ginkgo leaf in patients with coal-brunt arsenic.Methods Eighty-four patients of coal-brunt arsenic were randomly divided into two groups:treated group and control group.All the patients were treated for 3 months,patients in treated group with Ginkgo leaf while patients in control group with comfort tablets.Serum PAF and four hepatic fibrosis parameters were studied before and after treatment,and pathological study was given to some patients.Results The level of Serum PAF and the four hepatic fibrosis parameters were much lower in treated group after treatment than those before treatment (P<0.01).The effectual rate and total effective rate reached 17.5% and 42.5%,the difference was significant.The pathological examination showed certain improvement of liver in patients of treated group.Conclusions Ginkgo leaf tablet has the anti-hepatic fibrosis effect.
出处
《西南军医》
2005年第1期1-3,共3页
Journal of Military Surgeon in Southwest China
基金
全军"十.五"科研攻关面上项目
No :0 1MA0 48
成都军区"十.五"医药卫生科研课题 ( 0 1A0 0 1)
