摘要
目的 比较人类子宫肌层与子宫肌瘤局部催乳素 (PRL)水平的差异,探讨PRL对子宫肌瘤发生的作用。方法 收集人类子宫的肌瘤及子宫肌层组织 60例,应用免疫组化法检测PRL的表达。结果 子宫肌瘤及子宫肌层组织均有PRL的表达,子宫肌瘤的PRL表达水平高于肌层。结论 催乳素为人类子宫肌瘤及子宫肌层局部的一种生长因子,PRL也许与肌瘤的生长有关。
Objective To compare the difference of PRL expression in leiomyoma and myometrial,explore the effect of PRL on the development of leiomyoma.Methods We collect leiomyoma and myometrial tissues from 60 premenopausal woman who undergoing elective hysterectomy for symptomatic leiomyomas.Immunocytochemial method was carried out to detected the expression of PRL.Results Leiomyoma and myometrial cells were posively stained with PRL in cytoplasm.The positive rate in leiomyoma is higher than in myometrial cells.Conclusion Prolactin is an autocrine or paracrine growth factor for human myometrial and leiomyoma cells.PRL myabe regulate the growth of leiomyoma.
出处
《中原医刊》
2005年第2期1-2,共2页
Central Plains Medical Journal
