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细菌对碳青霉烯类抗生素耐药的机制及对策 被引量:3

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摘要 碳青霉烯类抗生素(亚胺培南、美罗培南等)1987年开始应用于临床,它是全新的β-内酰胺类抗生素,对革兰氏阴性菌和阳性菌、需氧菌和厌氧菌等均有超广谱、强效抗菌作用。二十世纪90年代以来广泛用于治疗未知病原体引起的重症感染,但随之出现了日益严重的细菌耐药性问题。铜绿假单胞菌、不动杆菌、肠杆菌科等细菌耐药报道有所增加,这些细菌导致的感染往往暴发流行,使治疗陷入无药可用的境地,
作者 范亚平
出处 《中国医学文摘(内科学)》 2005年第1期123-125,共3页 China Medical Abstracts
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