摘要
作者观察(1)76例未经抗棘球蚴药物治疗,手术摘除人肝(36例)、肺(40例)棘球蚴,其中有异常形态的肝囊8例(8/36,22.2％)、肺15例(15/40,37.5％)。(2)经丙硫咪唑治疗、手术摘除囊肿2例。(3)有异常形态的羊、牛及骆驼棘球蚴共38例,其中羊肝12例(12/35,34.2％)、肺10例(10/35,28.5％),牛肝4例(4/20,20％)、肺6例(6/20,30％),骆驼肝4例(4/10,40％)、肺2例(2/10,20％)。(4)人工感染杂交小白鼠106只,腹腔棘球蚴有异常形态者42例(42/106,42.4％)。这些异常形态结构多发生于角质层,生发层则罕见。囊壁表面也明显易见。它们的形态表现为:蜂巢状结构,斑块形成,皱折条纹,结节样变,棘状突形成,空泡形成,纹理改变,裂隙形成、波状纹,弹簧样纹理,结晶形成,不同区带形成,菜花样组织增生,局部性组织增生,纹理紊乱、破坏。
There have been many accounts of basic morphology of hydatid cysts in textbooks and medical journals, but few about the unusual morphology were reported. This paper reports (1)76 liver (36 cases) and lung (40 cases) hydatid cysts, who had not been treated with any anti-echinococcosis drugs. The unusual morphology observed in some cysts which are 8(8/36,22.2％) from human liver, 15(15/40,37.5％)from lung; (2)38 cases of unusual morphology cysts from sheep, cattles and camels, which are 12(12/35,40％) from liver of sheep、10(10/35,28.5％)from lung, 4 from cattle's liver (4/20,20％)、6 from lung (6/20,30％), 4 from liver of camel (4/10,40％)、2 from lung (2/I0,20 ~ ) and (3) 106 mice were experimental infection with protoscoleces intraperitoncally, 42 with unusual morphological aspects. In addition, there are 2 patients were treated with albendazole orally for 2 courses in a dosage of 18mg/kg/day, the sections of the cysts were compared with the untreated. The unusual morphological changes mainly appeared on the outer surface of the cystic wall and the laminated layer. They are:(1)fovealated tissue formation, (2)opaque spot formation, (3) wrinkle, (4)spinal process formation, (5) bubbles formation, (6)vein disordered and destruction, (7)hyaline degeneration, (8) granulation, (9) cauliflowre-like tissue proliferation, (10) spring-like veins degeneration, (11) ripply vein degeneration, (12) crevice formation, (13) crystalloid granulation, (14)nodulose degeneration and (15)local laminated layer tissue proliferation.
