摘要
目的 :探讨 2型糖尿病患者血、尿 β2 -微球蛋白 (β2 - MG)水平与早期肾脏损害的关系。方法 :采用放射免疫法 (RIA)测定 116例 2型糖尿病患者及 30例对照组的血、尿 β2 - MG含量。结果 :糖尿病组血及尿 β2 - MG水平均显著高于对照组 (P<0 .0 5或 P<0 .0 1) ,且病程越长其水平越高。结论 :血、尿β2 - MG检测有助于了解 2型糖尿病患者是否存在早期肾损害 ,对预防、治疗糖尿病肾病有重要意义。
Objective To explore the corelation betweenβ 2-MG(in blood and urine)and early damaga in kidney in type 2 diabetics.Methods RIA method was used to detect the level of β 2-MG (in blood and urine) in 86 cases of type 2 diabetes mellitus and 30 cases of control group respectively.Results The levels of β 2-MG(in blood and urine) in type 2 diabetes mellitus were higher than that in control group apparently(P<0.05 or P<0.01).The longer the period of type 2 diabetes mellitus was,the higher the β 2-MG level was.Conclusions The β 2-MG detected(in blood and urine) is contributed to early damage in kidney in type 2 diabetics,It is helpful in preventing and curing diabetic nephropathy.
出处
《实用医技杂志》
2005年第02A期306-307,共2页
Journal of Practical Medical Techniques
关键词
2型糖尿病
Β2-微球蛋白
糖尿病肾病
Type 2 diabetes mellitus
β2-MGicroglobulin
Diabetic nephropathy
