摘要
目的:观察莫西沙星 (拜复乐 )片剂门诊治疗慢性支气管炎急性加重期的疗效。方法:64例慢性支气管炎急性加重期患者随机分为2组 ,治疗组用莫西沙星400mg每日1次口服 ,治疗5天 ;对照组用阿莫西林500mg每日3次口服 ,治疗7天 ,观察临床指标、细菌学、临床疗效及安全性。结果 :治疗组与对照组的有效率分别为93.8 %和81.3 % ,细菌清除率为87.8 %和75.6 % ,两组比较差异有显著性 (P<0.05)。结论 :莫西沙星治疗慢性支气管炎急性加重期的疗效显著 ,是一种广谱。
Objective:To study the curative effect of moxifloxacin in the treatment of chronic bronchitis in acute exacerbation periˉod.Methods:Sixty-four cases with chronic bronchitis in acute exacerbation period were randomly divided into treatment group(moxifloxacin group)and control group(amoxycillin group),with32cases in each group.The curative effect and safety were compared between the two groups.Results:The effective rate and bacteria eradication rate were93.8%and87.8%respectively in moxifloxacin group and81.3%and75.6%respectively in amoxycillin group,with significant difference between them(P<0.05).Both groups had transient and slight side efˉfects.Conclusion:Moxifloxacin is a broad-spectrum and safe antibiotic and has significant effect in the treatment of chronic bronchitis in acute exacerbation period,and can be taken as the first choice drug on this disease.
出处
《现代医药卫生》
2005年第6期648-649,共2页
Journal of Modern Medicine & Health
