摘要
目的：研究临床常见致病菌对消毒剂的耐药性。方法：通过国家卫生部规定的消毒实验方法，检测44株医院感染病原菌对5种消毒剂的耐受情况，同时用标准菌、自然菌作参比以确定其耐药性。结果：从44株病及性细菌中分离出一株肺炎克雷白杆菌Ⅲ，该菌对5种消毒剂中的洗必太具有耐药性，并通过最小抑菌浓度（MIC）试验与最小杀菌浓度（MBC）试验，同时参照标准菌与自然菌的MIC与MBC予以证实。定量杀菌试验还进一步证实，为达到对耐药株的消毒合格标准（99．90％），则必须提高对消毒剂的常规应用浓度。本研究的耐药菌分离率为2．27％。结论：常见致病菌中确定存在对消毒剂耐药的菌株。
Objectivc: To study the drug resistance of common clinical pathogens to disintectants. Methods: The drug resis-tance of 44 strains of nosocomial infection pathogen were detected with disinfection method that Health Ministry determined.Meanwhile, it was compared with standard bacteria and natural bacteria to determine the durg resistance. Results: The Kleb-siella pneumonia Ⅲstrain was detected amoung 44 strains, which had drug resistance to chlorhexidinumin 5 disinfectants,passed (MIC) and (MBC) and also confirmed by comparing tests. This test further demonstrated that the routine disinfec-tant concentration should be increased to reach the standard drug resistant strain disinfection to 99. 90%. The separaterate of drug resistant strain was 2. 27%. Conclusion: The drug resistant strain to disinfectant does exist in common
出处
《黑龙江医学》
1999年第9期3-4,共2页
Heilongjiang Medical Journal
