摘要
介绍了雷公藤双层栓的制备和质量检查。雷公藤双层栓的上层为空白层,下层为含药层。空白层可有效地阻止后端所释药物向上扩散,从而避免相当部分药物经门肝系统吸收,因此可明显提高其生物利用度。
This paper introduces the preparation and quality examination of double-layer suppository of Tripterygium wilfordii Hook. F. This suppository includes both the upper layer(a blank layer) and the lower layer(a drug-containing layer). The former can effectivel resist drug(released from the suppository' s end )to diffuse up,which prevent from the absorption of a great part of drug through portal-hepatic system so that it' s bioavailability obviously rise.
出处
《中成药》
CAS
CSCD
北大核心
1993年第4期2-3,共2页
Chinese Traditional Patent Medicine
关键词
雷公藤
双层栓剂
制备
栓剂
剂型
Tripterygium wilfordii Hook. F., double-layer suppository, quality control, bioavailability
