摘要
选择双侧卵巢及子宫切除后１２～２４个月的妇女３０例，口服骨松宝３个月。用药前后对比发现，脊椎骨、股骨密度保持不变；与未用药组比较，明显抑制了骨吸收；尿钙与尿肌酐之比下降，血碱性磷酸酶下降，血磷升高，血钙无变化，血免疫球蛋白ＩｇＡ，ＩｇＧ水平升高，激素水平（Ｅ２、ＦＳＨ、ＬＨ）无变化，总胆固醇水平下降，甘油三酯水平下降，低、高密度脂蛋白胆固醇无变化。结果指出，中药骨松宝可提高免疫功能，调节钙磷代谢，保持骨质密度，改善骨质疏松程度，可用于治疗和预防骨质疏松，尤其对雌激素禁忌或慎用者（卵巢癌和子宫内膜腺癌。
Gusongbao was given for 3 months to 30 women had undergone bilateral oohorectomy and hysterectomy 12-24 months before. Compared with control group, we found no change in bone density of vertebrae and femur and significant inhibition of bone absorption. The ratio of calcium in urine and urinary creatinine, serum alkatine phosphatase and total cholesterol and triglyceride levels were decreased. The serum inorganic phosphorus and the levels of immunoglobulin IgA and IgG were increased. The blood calcium, the level of hormones(E2,FSH, LH) and low density lipoprotein cholesterol and high density lipoprotein cholesterol were not changed. It is concluded that the traditional Chinese medicine Gusongbao might increase the immunologic function, regulate calcium phosphorus metabolism, maintain bone density and improve osteoporosis can be used in therapy and prevention of osteoporosis and is especially suitable for ovarian carcinoma, carcinoma of endometrium and mammary cancer, in which administration of should be cautious or contraindicated.
出处
《中国骨质疏松杂志》
CAS
CSCD
1998年第4期56-59,共4页
Chinese Journal of Osteoporosis
