摘要
本文对30例正常未孕妇女,33例正常足月妊娠孕妇及28例妊高征孕妇采用双抗体PEG法测定血清T_3、T_4、TSH浓度,结果表明正常足月妊娠孕妇血清T_3浓度较正常未孕妇女显著增高(P<0.001),妊高征孕妇血清T_3浓度较正常孕妇显著降低(P<0.001),妊高征孕妇血清TSH浓度较正常孕妇显著增高(P<0.001),三组妇女血清T_4浓度差异不显著。同时妊高征妇女分娩小于胎龄儿者低T_3综合征发生率明显增高(P<0.05);轻、中度与重度妊高征孕妇血清T_4、T_3、TSH浓度比较无显著差异。提示妊高征孕妇甲状腺功能发生变化,推测妊高征孕妇IUGR及胎儿宫内窘迫发生率与血清T_3及TSH浓度有一定关系。
Serum concentrations of T_3, T_4, TSH were measured by radioimmunoassay in 30 cases of normal non--pregnant women, 33 cases of normal term pregnant women and 28 cases of patients with EPH-syndrome. It has been found that T_3 concentration of normal term pregnant omen was much higher than that of the normal non--pregnant women (P<0.001). Serum T_3 concentration of the patients with EPH--syndrome was much lower than that of the normal pregnant women (P<0.001). TSH concentration of patients with EPH--syndrome was much higher than that of normal term pregnant women (P<0.001). The difference of T4 concentration among the 3 groups was not remarkable. The patients with EPH-- syndrome who have given birth of small--for--estational age infants had significant high incidence of low-- T_3 syndrome P<0.05). The comparison among the serum T3, T4, TSH concentration of slight, moderate and severe EPH--syndrome patients had no obvious difference. These suggested that the thyroid function of the patients with EPH-syndrome had changed. Perhaps the incidence of IUGR and fetal distress in the paients with EPH--syndrome was assosciated with the serum T3 and SH concentration.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
1993年第5期285-286,共2页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
甲状腺功能
妊娠高血压
综合征
EPH—syndrome
Thyroid function
Small—for—gestational age infant
