摘要
本实验观察了迅速减压前呼吸模拟机载分子筛产氧系统不同富氧浓度的气体对狗高空迅速减压后气体交换功能的影响。按拉丁方的实验顺序,8条狗在减压前分别呼吸70％～100％4种富氧气体或空气5min,然后,再迅速减压到12000～18000m高度呼吸空气30s。实验结果表明,在减压后6～8s内,呼吸70％以上富氧浓度组的生理反应是等效的,表现在血氧饱和度和静脉氧分压的变化没有明显差别,但与空气对照组有显著差别。研究表明,高空迅速减压时氧自体内到体外的反向弥散分两个时相,它们与减压瞬间的生理效应和有效意识时间有密切的关系。这一结果是分子筛氧气装备工程设计与应用的基础。
The physiological effects on gas exchange functions of dogs were studied during rapid decompression (RD) at high altitudes after inhalation of various oxygen-rich gases which simulated those generated from the molecular sieve oxygen generating system (MSOGS) before RD. Eight dogs breathed the gases containing 70%-100% and 21% of oxygen respectively for 5 min according to the latin square design before RD and then breathed ambient air at the altitudes of 12 000-18 000m for 30s following RD. The results demonstrated that the physiological effects within 6-8 second after RD were equivalent when oxygen-rich gases with oxygen content higher than 70% were inhaled . There was no significant difference in the changes of the oxyhemoglobin saturation and venous oxygen partial pressure between different oxygen-rich groups, but significant difference was seen as compared with the group breathing air before RD. The study seems to indicate that the oxygen inversive diffusion from interior of body to environment after RD has two phases which are related with the time of effective consciousness and physiological effects. These results are the basis for the design and application of MSOGS.
出处
《中国应用生理学杂志》
CAS
CSCD
1993年第3期231-235,共5页
Chinese Journal of Applied Physiology
关键词
分子筛制氧系
富氧气体
迅速减压
molecular sieve oxygen generating system
oxygen-rich gas
alveolar gas
rapid decompression
fulminating hypoxia
