摘要
我们对50例生育力正常男性精浆中甘油-3-磷酸胆碱(GPC)、肉毒碱含量及α,1-4糖苷酶活力依次进行测定,结果显示:精浆中 GPC 与肉毒碱含量及α,1-4糖苷酶活力分别为2.32±0.65mmol/L、233.95±85.69μmol/L 及41.17±21.27IU/L,三者均呈显著正相关(P<0.01)。总量及总活力分别为7.35±3.04μmol/总毫升数、741.77±301.52nmol/总毫升数及133.93±88.35mIU/总毫升数(±s)。GPC、肉毒碱及α,1-4糖苷酶与精子在附睾内发育成熟均存在密切的联系,作为附睾重要的功能性指标,精浆中 GPC、肉毒碱含量及α,1-4糖苷酶活力的测定对附睾疾病的诊断与治疗都具有十分重要的意义。
Some markers of epididgmal function——glycerol-3-phosphorylcholine(GPC),L-carni- tine concentration and α,1-4 glucosidase activity were detected in seminal plasma from 50 fertile Chinese and their correlation were studied.The mean values of semen GPC,L-carnitine concentration and α,1-4 glucosidase activity were 2.32±0.65mmol/L,233.95±85.69μmol/L and 41.17±21.27 IU/L,and the total values of them were 7.35±3.04μmol/ejaculate,741.77±301.52nmol/ejaculate, and 133.93±88.35 mIU/ejaculate(±s)respectively.A significant positive correlation has been found between the concentrations of GPC and L-carnitine,the concentration of GPC and the activity of α,1-4 glucsidase(P<0.01). As a measure of epididymal function,the physiological roles of the GPC,L-carnitine and α,1-4 glu- cosidase related to the development and maturation of the sperm during epididymal transit have been discussed.
出处
《生殖医学杂志》
CAS
1993年第2期72-75,共4页
Journal of Reproductive Medicine
关键词
甘油
磷酸胆碱
肉毒碱
糖苷酶
精浆
附睾功能
Glycerol-3-phosphorylcholine(GPC)
L-carnitine
α,1-4 glucosidase
Seminal plasma
