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用单克隆抗体ELISA抑制试验诊断人体囊尾蚴病 被引量:2

Diagnosis Cysticercosis by Means of Inhibitory-ELISA Using Monoclonal Antibodies
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摘要 人体囊尾蚴病是一种严重危害人体健康的人兽共患寄生虫病。目前已建立了多种免疫诊断法,但因抗原成分复杂,尚不能完全排除假阳性反应。本文用特异单抗隆抗体以ELISA抑制法检测囊虫病人血清抗体,结果完全清除了假阳性反应,病人血清抗体检出率为85.80%(145/169)。 Cysticercosis is one of the harmful diseases to human beings.It is prevanlent in all over the world.Up to now,many immunodiagnosis methods have been established.But because of the complexity of the antigen, the false positive reaction can't be eliminated.Using the monoclone antibody we have established both specific site and unspecific site on the cysticercus cellulosae antigen. In this article,specific monoclone antibody was used by inhibitory-ELISA to detect the serological antibody of the cysticercosis patient.As a result,the false positive reaction was eliminated.The positive rate of cysticercosis patients was 85.80%(145/169).
出处 《哈尔滨医科大学学报》 CAS 1994年第4期280-282,共3页 Journal of Harbin Medical University
关键词 囊尾蚴病 单克隆抗体 ELISA Cysticercosis Monoclone antibody Inhibitory-ELISA Diagnosis
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