摘要
对胃镜下诊断为隆起糜烂性胃炎的50例病变处组织和14例"正常处"组织进行了透射电镜观察。在50例病变处组织中34例有不同程度的腺上皮形态结构改变;40例有腺上皮细胞之间炎细胞浸润;30例的腺腔内有幽门螺旋菌。在14例"正常处"组织中,腺上皮有轻度的形态结构改变;5例的腺上皮细胞之间有炎细胞浸润;2例的腺腔中有幽门螺旋菌。观察结果提示:隆起糜烂性胃炎是一种局灶性的,有炎细胞浸润、固有膜及粘膜下水肿、血浆渗出的慢性炎症。幽门螺旋菌可能是该病的主要病因之一。
cases of convex erosive gastritis(CEG)tissues and 14 cases of 'normal spot'tissues were observed under TEM. It is shown that 30 of them have Campylobacter pyioridis(CP)infection in the glandular cavities,34 obvious gastric epithelium structure changes and 40 inflammatory cell invasion between glandular epithelium cells. In the matrix of the tissues,lymphocyte,plasmacell,neutrophilic granulocyte,mast cell and phagocyte invasion are indicated respectively in 42,39,38,30 and 28 cases.But the CP infection rates and the pathologic change degrees in ' normal spot'tissues are lower than those in convex erosive spot tissues.The results show that CEG is a special chronic gastritis with various inflammatory cell invasions,lamina propria and tela submucosa edema. CP may be one of its important pathogenesis,Certain immunologic mechanism may involve the pathologc change process of this disease.