摘要
以１／５０００ＬＤ５０、１／１０００ＬＤ５０和１／１００ＬＤ５０的氯化甲基汞剂量分别给雄性小白鼠经口染毒７５天后，测定睾丸组织中的ＬＰＯ和ＬＤＨ－ｘ。结果表明，实验组的ＬＰＯ高于对照组；１／１０００ＬＤ５０和１／１００ＬＤ５０组的ＬＤＨ－Ｘ均低于对照组和１／５０００ＬＤ５０组；睾丸脏器系数各组间无差别。同时探讨了甲基汞造成雄性动物生殖能力下降的可能机制。
Mice were administered MeHg via oral at doses of 1/5000 LD(50),1/1000LD(50) and 1/100LD(50) respectively for 75 days.The results showed that LPO of the mice treated with MeHg was higher than the control.There was marked reduce for LDH-x activity in the treated groups of 1/1000 LD(50) and 1/100 LD(50) compared with the control(P<0.05).Meanwhile,it was studied that the possible mechanism of the reproductive toxicity induced by MeHg in mice.
出处
《环境与健康杂志》
CAS
CSSCI
CSCD
北大核心
1994年第4期150-151,共2页
Journal of Environment and Health
