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高原人体血中肌红蛋白、乳酸和氨与劳动能力的关系 被引量:4

A STUDY OF THE RELATIONSHIP OF BLOOD LEVEL OF MYOHEMOGLOBIN LACTIC ACID AND AMMONIUM WITH HIGH ALTITUDE LABOR CAP ACITY OF HUMAN BEINGS
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摘要 以11名健康男青年在低压舱内模拟在3500m和4500m高度劳动并与平原自身对照比较,发现海拔愈高血氧饱和度和劳动效率下降愈明显(P<0.01),呈现前者降1%后者降2%趋势,经复合锻炼后两者有明显提高(P<0.05)。血内Mb、LA和BA的水平与劳动能力的降低和恢复呈负相关变化,提示反映劳动能力的乳酸性氧债和非乳酸性氧债(Mb)可作为判断高原劳动能力的灵敏指标;BA可反映肌肉运动时需依赖的肌球蛋白和肌动蛋白的消耗分解。上述结果表明,高原劳动能力下降,与两类氧债增大和富含氨基酸蛋白分解大于合成有关。 he labor capacity of 11 young healthy males were determined at sealevel and at simulated high altitudes of 3500 and 4500m in a hypobaricchamber.It was found that the higher the altitude,the more obvious reduc- tion of the blood saturation of oxygen and the labor norm (p<0.01).Ther0Was 1% reduction of the former occurring simultaneously with 2%reduc-tion of the latter.After comprehensive physical training of the young menat a high altitude, the blood saturation of oxygen and the labor norm weresignificantly improveed(P<0.05). The changes of blood levels of myohemo一globin,lactic acid and ammoniuin were negatively correlated with those oflabor norm。It is known that lactic acid oxygen debt and non一lactic acid(myohemoglobin)oxygen debt can be used as sensitive indices to assess thelabor norm at high aItitude and blood ammonium can reflect the breakingdown of myosin and actin on which the muscular movement is depended。Our findings indicate that the reduction of labor capacity at high altitude isclosely related to the increase of the 2 oxygen debts and to the ammoniuminduced by excessive breaking down of the proteins,which exceeds their syn-thesis。
出处 《解放军预防医学杂志》 CAS 北大核心 1994年第6期427-431,共5页 Journal of Preventive Medicine of Chinese People's Liberation Army
关键词 高原 肌红蛋白 劳动能力 军队劳动卫生 high altitude,myohemoglobin,labor norm
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