摘要
分析８４例慢性病毒性肝炎患者和２０例正常对照者血浆氨基酸的检测结果。慢性迁延型肝炎（ＣＰＨ）和慢性活动型肝炎（ＣＡＨ）患者的血浆支链氨基酸（ＢＣＡＡ）、芳香族氨基酸（ＡＡＡ）和天冬氨酸、丝氨酸、谷氨酸、丙氨酸、蛋氨酸均较正常对照织显著升高（Ｐ＜０．０５～０．０１）；但ＢＣＡＡ／ＡＡＡ比值与正常对照组比较，ＣＰＨ组无显著变化（Ｐ＞０．０５），而ＣＡＨ组显著降低（Ｐ＜０．０１）．提示，观察慢性病毒性肝炎患者血浆氨基酸的变化，特别是ＢＣＡＡ／ＡＡＡ比值的变化，对于慢性肝炎的临床分型、了解肝损程度、判断预后及指导临床治疗均有一定意义。
This paper analysed the experimcntal results of plasma amino acid of 84 cases of chronic viral hepatitis and 20 cases of normal controls.The information indicated that comparing with normal controls branched-chain amino acid (BCAA),aromatic amino acid (AAA),ASP,SER,GLU,ALA and MET obviously increased in the patients with chronic persistence hepatitis(CPH)and chronic active hepatitis(CAH)(P<0.05～0.01),but the changes of BCAA/AAA ratio was not obvious in CPH(P>0.05)and the ratio evidently decreased in CAH(P<0.01).All these suggest that observing the changes of plasma amino acid,espccially BCAA/AAA ratio,has certain significance for the clinical classification,understanding the damage degree of the liver,judging the prognosis and guiding the clinical treatrment.
出处
《南通医学院学报》
1994年第4期440-442,共3页
ACTA Academiae Medicinae Nantong
关键词
慢性
病毒性肝炎
血浆
氨基酸
chronic viral hepatitis,plasma amino acid
BCAA/AAA ratio
