摘要
应用ＡＢＣ法，以酪氨酸羟化酶作为标记物，对幼年、成年、老年Ｗｉｓｔａｒ大鼠（每组各１０只）脑实质内血管的免疫阳性神经纤维的分布类型、纤维密度等进行了观察。结果是：在三组不同年龄大鼠脑皮质血管壁上均出现免疫反应阳性纤维。幼年鼠脑皮质血管神经纤维分布类型有环行型（占５８．１４％）和纵行型（占４１．８６％），纤维密度较小；成年鼠分布类型主要有网状型（占８９．１２％），其次为环行型（占８．３４％），少数为纵行型，纤维密度较大；老年鼠分布类型大多数为环行型（７６．０３％），其余为网状型（占２３．９７％），纤维密度明显较成年鼠稀疏。本文讨论了脑内血管神经纤维的分布类型、纤维密度与脑内微循环的神经源性调节的关系。
In order to observe the distribution and density of the catecholamine nerve fibers in the wall of the intracerebral vessels of infant, adult, aged rat (10 for each group), it was used with ABC immunoperoxydase techniques, employing Tyrosine-hydroxylase (TH) as label. The immunoreractive positive fibers, brown, was found on the wall of the intracerebral vessels of rat at different age groups. The type of distribution of catecholamine nerve in the infant rat was longitudinal (41. 86% ) and circular (58.14%) , of the adult mostly reticular (89.12%). partly circular (8.34%), and of the aged mostly circular (76. 03%). Partly reticular (23.97%), with P<1.01. indicating significant difference among the three age groups. The density of fibers in the infant was lower, of the adult higher, and of the aged in between. These results suggest that the longitudinal and the circular was simple , immature and the reticular was complex, mature. The latter was more sufficient than the former in regulating the cerebral blood flow. The relationship between the type of distribution and of density of fibers of monoamine nerve in intracerebral vessels and their nerve regulation was discussed.
出处
《神经解剖学杂志》
CAS
CSCD
北大核心
1994年第3期255-257,共3页
Chinese Journal of Neuroanatomy
关键词
脑血管
免疫组织化学
酪氨酸羟化酶
神经纤维
intracerebral vessels, catecholaminergic nerve, immunohistochemistry, Ontogeny
