摘要
脑肿瘤细胞生长速率加快,能量代谢、氨基酸转运和蛋白质合成旺盛。联合18F-FDG与11C-MET的PET,比单一显像剂更有助于脑肿瘤的组织学分级、术后复发和疗效评价。11C-MET较18F-FDG能更精确地显示肿瘤扩散范围和轮廓,对制订手术和立体定向放疗计划有重要意义,是常规CT和(或)MRI的有益补充。
Energy metabolism and amino acid transport and incorporation are important components of the pathophysiology of brain tumors. Combination of 18F-FDG and amino acid, especially 11C-MET is more useful than single tracer in the field of brain tumor grading, differential diagnosis recurrent tumor from radiation necrosis and evaluation of prognosis. In addition, 11C-MET is better than 18F-FDG in delineating tumor boundary, so it can provides more exact information in biopsy localization and planning of radiosurgery.
出处
《国外医学（放射医学核医学分册）》
2005年第1期10-14,共5页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
