摘要
目的评价伊贝沙坦对心房颤动(房颤)患者恢复窦性心律(复律)后的维持作用。方法持续性房颤患者52例,随机分为两组各26例。两组经正规抗凝治疗3周后均给予胺碘酮200mg,q8h,用1周后继以200mg,q12h,1周后改为200mg·d1,治疗组同时给予伊贝沙坦150mg·d1。分别观察两组中成功复律者中的复发率。结果随访6个月,治疗组复律19例中有2例复发,17例维持窦性心律;对照组复律17例中有8例复发,9例维持窦性心律。治疗组房颤复发率低于对照组(P<005)。结论伊贝沙坦能降低房颤复发率,有效维持窦性心律。
Objective To evaluate the effect of irbesartan to maintain sinus rhythm in patients with durative atrial fibrillation after cardioversion. Methods Fifty-two patients with durative atrial fibrillation were randomized into two equal groups. Group I were treated with amiodarone, and group Ⅱ were treated with amiodarone plus irbesartan. The reoccurence of atrial fibrillation was observed in all the patients for 6 mo after cardioversion. Results The reoccurence of atrial fibrillation in group I was higher than that in group Ⅱ. Conclusion The results suggest that irbesartan may reduce the reoccurrence of atrial fibrillation and be efficacious in maintaining sinus rhythm.
出处
《医药导报》
CAS
2005年第3期187-188,共2页
Herald of Medicine
关键词
伊贝沙坦
胺碘酮
心房颤动
Irbesartan
Amiodarone
Atrial fibrillation
