期刊文献+

表皮生长因子治疗慢性萎缩性胃炎 被引量:3

TREATMENT OF CHRONIC ATROPHIF GASTRITIS WITH EPIDERMAL FACTOR
下载PDF
导出
摘要 取人胃粘膜上皮细胞置RPMII640培养液中培养,表皮生长因子(EGF)组加EGF,对照组加培养液,结果显示EGF有促进细胞DNA合成作用P<0.0001)。97例慢性萎缩性胃炎(CAG)随机分为治疗组(55例)和对照组(42例),治疗组用EGF+得乐治疗、对照组单用得乐治疗。6个月后经胃镜和病理活检复查,结果:治疗组对CAG及肠化疗效明显优于对照组(P<0;01)。EGF无毒副作用。 7 cases of chronic atrophic gastritis(CAG)were randomly divided into treatment group(55 cases)and control group(42 cases).The treatment group was treated with EGF plus DeNoland the control group with DeNol only,Gastroscopy and biopsy were performed for checking af-ter 6 months. The results suggested that the therapeutic effects of CAG and intestinal metaplasia(IM)on the treatnment group were significantly better than on the control group(P<0.01). EGF has no toxic side-effects.
出处 《温州医学院学报》 CAS 1994年第4期205-207,共3页 Journal of Wenzhou Medical College
关键词 表皮生长因子 慢性萎缩性胃炎 DNA合成 肠化 epidermal growth factor DNA sysnthesis chronic atrophic gastritis intestinalmetaplasia(IM)
  • 相关文献

参考文献1

二级参考文献7

  • 1Scheving LA,et al.Circadian phase-dependent stimulator effect of epidermal growth factor on deoxyribonucleic acid synthesis in the duodenum,jejunum,ileum,caecum,colon and rectum of adult male mouse. The Journal of Endocrinology . 1980
  • 2Kirkegaard P,et al.Effect of vasoactive intestinal polypeptide and somotostatin on secretion of epidermal growth factor and bicarbonate from Brunner’s gland. Gut . 1984
  • 3Olsen PS,et al.Oral administration of synthetic human urogartrone promotes healing of chronic duodenal ulcers in rats. Gastroenterology . 1986
  • 4Konturek SL,et al.Gastric cytoprotection by epidermal growth factor. Gastroenterology . 1981
  • 5Konturek SJ,et al.Role of mucosal prostaglandins and DNA synthesis in gastric cytoprotection by luminal epidermal growth factor. Gut . 1981
  • 6Savage CR,et al.The primary structure of epidermal growth factor. Journal of Biological Chemistry . 1972
  • 7Gregory H.Isolation of urogastrone and its relationship to epidermal growth factor. Nature . 1975

共引文献3

同被引文献60

引证文献3

二级引证文献23

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部