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尿激酶型纤溶酶原激活物受体与炎性关节病 被引量:3

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摘要 尿激酶型纤溶酶原激活物受体(uPAR)与其配体尿激酶型纤溶酶原激活物(uPA)介导的细胞外基质蛋白裂解作用与炎性关节疾病中关节软骨和骨的破坏密切相关。本文就uPAR的结构与功能及其在炎性关节病中的病理作用、临床应用等方面的研究进展进行综述。
出处 《国外医学(内科学分册)》 2005年第3期123-125,129,共4页 Foreign Medical Sciences(Section of Internal Medicine)
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  • 1何斌,史晨辉,王永明.尿激酶型纤溶酶原激活物系统与软骨降解[J].农垦医学,2005,27(3):229-231. 被引量:3
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  • 3周京国,郭晓兰,唐中,袁国华,魏锦,杨明辉,何兰,蒋红.可溶性尿激酶型纤溶酶原激活物受体在RA患者血浆和滑液的水平及其临床意义[J].中华风湿病学杂志,2006,10(12):713-716. 被引量:5
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