摘要
目的 了解鲍曼不动杆菌在医院的分布 ,动态观察其耐药性发展情况 ,为临床合理应用抗生素提供依据。方法 用法国生物梅里埃公司的API及VITEK2鉴定系统对临床分离菌株进行鉴定 ,用K- B纸片扩散法进行药敏试验 ,用WHONET5软件对药敏结果进行统计学分析。结果 鲍曼不动杆菌对所监测的 11种抗生素均有不同程度的耐药 ,动态观察其耐药率有逐渐增高的趋势 ,尤以 2 0 0 3年增高最为明显 ,重症监护室 (ICU)的耐药率明显高于非ICU。结论 多重耐药的鲍曼不动杆菌感染在临床上呈上升趋势 ,尤其在ICU ,使临床医生对鲍曼不动杆菌感染的治疗越来越棘手 ,因此对鲍曼不动杆菌进行规范的连续的耐药监测 ,及时发现耐药菌株 ,对临床调整治疗方案、预防医院感染的发生是十分重要的。
Objective Finding out the distribution of Acinetobacter baumannii Bouver et Grimont in the hospital and observing its drug resistance dynamically in order to provide evidence to proper use of antibiotics in clinics.Methods Acinetobacter baumannii was identified by BioMerieux API system and drug sensitive tests were performed by K-B test,the data were analyzed by WHONET5 software.Results A.baumannii had various drug resistances to 11 antibiotics,which were monitored and proved tending to strengthen especially in 2003.The resistance rate in the intensive care unit (ICU) was distinctly higher than the others.Conclusion The infection of multi-drug resistant A.baumannii in clinic had ascending tendency, especially in ICU.The infection of A.baumannii was one of the most complex problems. Therefore, monitoring A.baumannii constantly and regularly, finding out resistant strains timely,and adjusting the treatment regimen was very important to the prevention of nosocomial infection.
出处
《山西医药杂志》
CAS
2005年第3期201-202,共2页
Shanxi Medical Journal
