摘要
目的 :研究木贼科植物笔管草 (Equisetumdebile)的化学成分。方法 :采用硅胶、sephadexLH 2 0凝胶柱色谱进行分离纯化 ,通过理化方法和光谱分析鉴定化合物结构。结果 :从笔管草全草乙酸乙酯和正丁醇提取物中分离得到 4个megastigmane型化合物和 4个黄酮苷 ,分别鉴定为blumenolA(1) ,corchoinosideC(2 ) ,sammangaosideA(3) ,(3S ,5R ,6R ,7E ,9S)- megastigmane-7-ene-3-hydroxy-5 ,6-epoxy-9-O-β- D-glucopyranoside(4) ,山柰酚-3,7-双葡萄糖苷 (5 ) ,camelliasideC(6 ) ,山柰酚-3-槐糖苷 (7)andclematine(8) .化合物 1-4 ,6 。
AIM: To study the chemical constituents of Equisetum debile. METHODS: Compounds were isolated by column chromatography on silica gel, sephadex LH-20, ODS-18 and their structures were elucidated based on the spectroscopic methods including 2D NMR (COSY, HMQC, HMBC). RESULTS: Four megastigmane type compounds were isolated, one aglycone and three glucosides, identified as blumenol A (1), corchoinoside C (2), sammangaoside A (3), and (3S, 5R, 6R, 7E, 9S)-megastigmane-7-ene-3-hydroxy-5, 6-epoxy-9-O-β-D- glucopyranoside (4). Four flavonoid glycosides, kaempferol-3, 7-di-β-D-glucoside (5), camelliaside C (6), kaempferol 3-O-β-sophoroside (7), clematine (8) were also obtained from this plant. CONCLUSION: All megasigmane compounds and compound 6, 8 were obtained from Equisetaceae family for the first time.
出处
《中国天然药物》
SCIE
CAS
CSCD
2005年第2期93-96,共4页
