摘要
目的 确定促肝细胞生长素用细菌内毒素检查法替代家兔法的可能性。方法 对样品进行干扰试验研究。结果 促肝细胞生长素溶液不存在干扰作用 ,而注射用促肝细胞生长素存在明显的增强作用 ,且难以通过稀释法消除这种干扰。结论 促肝细胞生长素溶液可用细菌内毒素检查法替代热原检查法进行质量控制 ,但注射用促肝细胞生长素仍需用家兔法对其进行热原检验。
Aim To ensure the possibility that bacterial endotoxins test replaces rabbitts test in hepatocyte growth promoting factor. Methods The disturbance of patterns was studied in this paper. Results The results showed that hepatocyte growth promoting factor solution has no disturbance, but hepatocyte growth promoting factor for injection has obvious enhancement and the disturbance can’t be eliminated by dilute patterns. Conclusion Bacterial endotoxins test can be used in hepatocyte growth promoting factor solution and it can't be used in hepatocyte growth promoting factor for injection.
出处
《安徽医药》
CAS
2004年第4期291-292,共2页
Anhui Medical and Pharmaceutical Journal
